CIP/SIP Skid Plants/Vessels

CIP/SIP Skid Plants/Vessels

CIP/SIP Skid Plants/Vessels

CIP/SIP Skid Plants / Vessels

cip/sip skid for cleaning manufacturing plants vessels
CIP/SIP Skid Plants / Vessels

At Kyra International, a top CIP & SIP Skid Manufacturer & Exporter & Supplier in Mumbai, India, we specialize in delivering modular process skids that combine Clean-in-Place (CIP) and Sterilize-in-Place (SIP) functionality. Our CIP/SIP Skid is designed to automate your cleaning and sterilization cycles, ensuring effective, validated, pollutant-free operations that meet strong pharmaceutical or biotech standards.

When your production lines handle sensitive formulations, be it sterile injections, oral liquids, or topical creams, the way you clean your equipment is just as critical as how you manufacture. With our CIP/SIP skid, you get a safe, repeatable, and documented way to keep your process hygienic without disassembling your system.

What Is a CIP/SIP Skid?

Cleaning-In-Place (CIP) and Sterilization-In-Place (SIP) are systems designed for automatic cleaning and purification without major disassembly and assembly work. We design, develop, manufacture, supply and install Mobile CIP/SIP Skid and Fixed these Units for sanitization and sterilization. The units are custom-made, modular, skidded in automated or semi-automated Models as per the required time cycle for cleaning and sterilization as a part of cGMP requirements, from adjustable to large fixed Multi-Tank systems.

Why a CIP/SIP Skid Matters

Imagine a pharmaceutical facility in Mumbai or India, running multiple batches of injectables and suspensions. Between batches, you need to clean vessels, pipes, filters, and transfer lines. Manually taking everything apart, cleaning, and reassembling, it's time-consuming, defective and risky for contamination. Enter the CIP/SIP skids, which simplify all of this:

  • Automated cleaning (CIP) allows cleaning of internal surfaces without disconnection.
  • Automated sterilization (SIP) uses steam or other methods to sterilize in place, reducing microbial risk.
  • It’s skid-installed, fully integrated on a frame, pre-tested, and ready to plug into your plant.
  • This means less downtime, safer operations, and a higher standard.
Cip/sip Skid for Cleaning Manufacturing Plants/vessels
Key Features
  • Sanitary Design to meet all cGMP criteria.
  • CIP systems are made as per specific application, facility layout and utility.
  • Automation as per MCA & USFDA 21 CFR Part 11.
  • Effective and efficient process equipment cleaning.
Advantages & Benefits of Kyra’s CIP/SIP Skid System

Cleaning-In-Place (CIP) and Sterilization-In-Place (SIP) are systems designed for automatic cleaning and purification without major disassembly and assembly work. We design, develop, manufacture, supply and install Mobile CIP/SIP Skid and Fixed these Units for sanitization and sterilization. The units are custom-made, modular, skidded in automated or semi-automated Models as per the required time cycle for cleaning and sterilization as a part of cGMP requirements, from adjustable to large fixed Multi-Tank systems.

Why a CIP/SIP Skid Matters
  • Increased Safety & Hygiene: Automated cleaning reduces human contact and risk of pollutants.
  • Regulatory Compliance: Designed for GMP, with control over critical guidelines and detailed cycle records.
  • Repeatability: Defined, validated cleaning cycles ensure consistent cleanliness across every batch.
  • Effectiveness: Faster cleaning, lower utility usage, and less chemical consumption.
  • Reduced Downtime: CIP/SIP systems enable fast integration and minimal installation difficulty.
  • Sustainability: Closed loops and recirculation options cut down on water and chemical waste.
  • Cross-Contamination Control: Accurate CIP/SIP designs minimize the risk of remains and microbial carryover.
Use Cases & Applications

Kyra’s CIP/SIP skid is ideal for industries where hygiene, sterility, and repeatable cleaning are critical:

  • Pharmaceutical Manufacturing: Injectable lines, fermenters, buffer tanks, filling lines.
  • Biotech / Biopharma: Bioreactors, downstream processing skid lines, sterile fluid lines.
  • Cosmetic & Personal Care: Manufacturing lines for lotions, creams, gels, and emulsions.
  • Food & Dairy: High hygiene processes in dairy, beverages, or clean-label food production.
  • Nutraceuticals: Skid systems for supplement liquid production, herbal syrups, etc.
Why Choose Kyra International for CIP/SIP Skid?
1. Expertise in Pharma Process Equipment

As a Manufacturer & Exporter & Supplier in Mumbai, India, Kyra International has great engineering experience in building sip process skids for regulated industries.

2. Customization for Your Needs

We work with you to design the skid based on your process flow, number of cleaning circuits, cycle time, and validation requirements.

3. Pre-Commissioning & Testing

Our CIP/SIP skids are fully built, wired, and FAT (Factory Acceptance Tested) before delivery, ensuring quick and smooth installation at your site.

4. Validation Support

We support DQ, IQ, OQ, and PQ documentation and help set up validation protocols (conductivity checks, riboflavin tests, etc.).

5. Service & Maintenance

Our Mumbai-based support team provides installation, commissioning, training, and periodic maintenance, minimizing your risk and maximizing uptime.

FAQ — CIP / SIP Skid

A “CIP/SIP skid” is a modular frame-mounted system that automates Clean-in-Place (CIP) and Sterilize-in-Place (SIP) operations for process equipment, like tanks and piping, without needing to disassemble them. .

Automated CIP/SIP significantly reduces downtime, minimizes human error and pollutants risk, provides repeatable and validated cleaning cycles, and helps meet regulatory standards.

Yes, Kyra’s skid supports validation protocols, including riboflavin tests for CIP, temperature mapping for SIP, and generates batch records for regulatory standards.

We use SS 316L stainless steel for all product-contact surfaces, polished or electropolished, and orbital welds for hygienic joints.

Yes. We offer fully automated skid-installed systems with PLC + HMI control, cycle recipe management, and data recording.

Definitely. The skid is designed for effective use of water, detergent, and steam; closed-loop recirculation reduces waste, and optimized cycles reduce utility consumption.

The closed-loop skid design cleans only the intended circuits, controls concentration and flow, and sterilizes lines with steam to reduce remaining microbes.

Yes. We can design the skid for single or multiple cleaning circuits, depending on how many vessels or lines you need to clean, and whether you want centralized or decentralized cleaning.
Conclusion: Your Clean & Sterile Partner

Kyra International’s CIP/SIP Skid isn’t just a piece of equipment; it’s your partner in maintaining hygiene, efficiency, and regulatory compliance throughout your manufacturing process. Whether you run a sterile injectable facility, a biotech plant, or a multi-product cosmetic line, our skid delivers validated cleaning cycles, repeatability, and safety, all supported by our engineering team in Mumbai, India.

Let’s talk about your cleaning needs. Reach out to us for a detailed design, FAT, and validation plan, and let’s bring clean, sterile production to your facility.

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Building No 1, Shripal One, 313, Golani Naka, Vasai East, Mumbai, Maharashtra 401208

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